SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells
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چکیده
منابع مشابه
SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells.
The packaging of DNA into chromatin plays an important role in transcriptional regulation and nuclear processes. Brahma-related gene-1 SMARCA4 (also known as BRG1), the essential ATPase subunit of the mammalian SWI/SNF chromatin remodeling complex, uses the energy from ATP hydrolysis to disrupt nucleosomes at target regions. Although the transcriptional role of SMARCA4 at gene promoters is well...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2016
ISSN: 1088-9051,1549-5469
DOI: 10.1101/gr.201624.115